Mel C. Jackson, Ph.D.
Director of Product Development & Services Pesticide Analysis, Analytical Methods Development, Biochemistry, Environmental Monitoring, Safety Officer (808) 621-1383 mjackson@harc-hspa.com |
Academic Qualifications
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Current Research
Coordinates research projects with potential for intellectual property development and commercialization. Initiated new Botanics Department, specializing in botanical extraction method development. Developed HPLC methodology (proprietary) for analyzing kava, shampoo ginger and other gingers. Set up contract service for kava and stevia growers to obtain analyses at cost. Supervises, conducts, and reports on chemical research on substances important to the agricultural industry. Adapts or develops and evaluates analytical methodology for crop protection chemicals to be used on crops in Hawaii and elsewhere. Supervises and coordinates any field-related and/or lab.-related activities. Consults with growers to evaluate the use of chemicals. Provides analytical services interdepartmentally, for chemical manufacturers, Interregional Project No. 4, and other sponsors. Develops and implements methodology for crop protection chemical metabolism studies. Coordinates station involvement in minor crop pesticide registration activities. Involved in environmental projects including leaching studies, monitoring of water quality and movement of crop protection chemicals away from target areas. Implements radiation safety policies and reviews protocols for all field and lab. related radioisotope use.
Selected Publications
Jackson, M.C. (1999). B-Ala-His dipeptidase, in Handbook of Proteolytic Enzymes, chapter 13, Eds. Woessner J.F. Jnr. & Barrett, A.J. Academic Press.
Jackson, M.C. & Lenney, J.F. (1996). The distribution of carnosine and related dipeptides in rat and human tissues. Inflamm. Res. 45, 132-135.
Jackson, M.C., Richmond, J. & Lenney, J.F. (1994). Homocarnosine (GABA-His): Preliminary cvidencc for a neuroregulatory role in the CNS . Society for Neuroscience Abstracts, 24th Annual Meeting, 517.
Jackson, M.C., Scollard, D., Mack, R. & Lenney, J.F. (1994). Localization of a novel pathway for the release of GABA in human CNS. Brain Res. Bull. 33, 379-385.
Jackson, M.C., Hardman, J.M. & Lenney, J.F. (1993). Immunohistochemical evidence for the release of GABA via the hydrolysis of neuronal homocarnosine. Society for Neurosciences Abstracts, 23rd Annual Meeting, 1151.
Jackson, M.C. & Lenney, J.F. (1992). homocarnosinosis patients and great apes have a serum protein that cross-reacts with human serum carnosinase. Clin. Chim. Acta. 205 109-116.
Jackson, M.C., Kucera, C.M., Lenney J.F. (1991). Purification and properties of human serum carnosinase. Clin. Chim. Acta. 196, 193-20S.
Jackson, M.C., Kucera, C.M., Lenney J.F. (1990). Purification and Characterization of serum carnosinase. FASEB J. 4, 2157.
Jackson, M.C., Choudry, Y., Woodley, J.F. & Kenny, A.J. (1988). A fluorimetric assay for aminopeptidase W. Biochem J. 253, 299-302.
Jackson, M.C. (1988). "A Study of the Small Intestinal Brush Border Peptidases of the Rat Small Intestine" Ph.D. Thesis, University of Keele, U.K.
Coordinates research projects with potential for intellectual property development and commercialization. Initiated new Botanics Department, specializing in botanical extraction method development. Developed HPLC methodology (proprietary) for analyzing kava, shampoo ginger and other gingers. Set up contract service for kava and stevia growers to obtain analyses at cost. Supervises, conducts, and reports on chemical research on substances important to the agricultural industry. Adapts or develops and evaluates analytical methodology for crop protection chemicals to be used on crops in Hawaii and elsewhere. Supervises and coordinates any field-related and/or lab.-related activities. Consults with growers to evaluate the use of chemicals. Provides analytical services interdepartmentally, for chemical manufacturers, Interregional Project No. 4, and other sponsors. Develops and implements methodology for crop protection chemical metabolism studies. Coordinates station involvement in minor crop pesticide registration activities. Involved in environmental projects including leaching studies, monitoring of water quality and movement of crop protection chemicals away from target areas. Implements radiation safety policies and reviews protocols for all field and lab. related radioisotope use.
Selected Publications
Jackson, M.C. (1999). B-Ala-His dipeptidase, in Handbook of Proteolytic Enzymes, chapter 13, Eds. Woessner J.F. Jnr. & Barrett, A.J. Academic Press.
Jackson, M.C. & Lenney, J.F. (1996). The distribution of carnosine and related dipeptides in rat and human tissues. Inflamm. Res. 45, 132-135.
Jackson, M.C., Richmond, J. & Lenney, J.F. (1994). Homocarnosine (GABA-His): Preliminary cvidencc for a neuroregulatory role in the CNS . Society for Neuroscience Abstracts, 24th Annual Meeting, 517.
Jackson, M.C., Scollard, D., Mack, R. & Lenney, J.F. (1994). Localization of a novel pathway for the release of GABA in human CNS. Brain Res. Bull. 33, 379-385.
Jackson, M.C., Hardman, J.M. & Lenney, J.F. (1993). Immunohistochemical evidence for the release of GABA via the hydrolysis of neuronal homocarnosine. Society for Neurosciences Abstracts, 23rd Annual Meeting, 1151.
Jackson, M.C. & Lenney, J.F. (1992). homocarnosinosis patients and great apes have a serum protein that cross-reacts with human serum carnosinase. Clin. Chim. Acta. 205 109-116.
Jackson, M.C., Kucera, C.M., Lenney J.F. (1991). Purification and properties of human serum carnosinase. Clin. Chim. Acta. 196, 193-20S.
Jackson, M.C., Kucera, C.M., Lenney J.F. (1990). Purification and Characterization of serum carnosinase. FASEB J. 4, 2157.
Jackson, M.C., Choudry, Y., Woodley, J.F. & Kenny, A.J. (1988). A fluorimetric assay for aminopeptidase W. Biochem J. 253, 299-302.
Jackson, M.C. (1988). "A Study of the Small Intestinal Brush Border Peptidases of the Rat Small Intestine" Ph.D. Thesis, University of Keele, U.K.